John Sninsky brings a comprehensive and deep understanding of the development and application of pioneering molecular procedures to the translation of research-grade biomarker assays into clinical-grade clinically adopted diagnostic tests. He has authored over 110 scientific papers including advanced methods in molecular biology, lipid sub-fractionation, application of the polymerase chain reaction (PCR) to virology and cancer, and genome-wide genetic association studies for multiple common, complex diseases. Most recently, as CSO of CareDx (Nasdaq: CDNA) John oversaw the translation of an early stage research NGS Test to a US government reimbursed and now widely adopted Laboratory Developed CLIA-CAP test for transplanted kidney rejection. Over the last year, John has consulted in Dx assay development and advised on clinical and technical dossier drafting for reimbursement in cancer, autism, and liver disease. He advises commercial translation efforts at Stanford University (SPARK) and University of California in San Francisco (CATALYST).
John holds a PhD from Purdue University and carried out postdoctoral studies at Stanford University before serving on the faculty of Albert Einstein College of Medicine.
He has over 30 years experience having served in executive positions at Cetus, Roche Molecular Systems, Hoffmann La-Roche, Celera, Quest Diagnostics and CareDx . These companies ranged from small to enterprise CLIA-CAP laboratories and small to enterprise in vitro diagnostic (IVD) companies that required FDA clearance and approval for commercialization of kits.
John’s past awards include being a recipient of the Purdue University Distinguished Alumni Award (2001), the Hoffmann-La Roche R & D Prize (1997) for his efforts in applying PCR to virology and developing assays for measuring viral load in individuals with (HIV) AIDS, the Pan American Society for Clinical Virology Award (1992) and the Centers for Disease Control Charles C. Shepherd Science Award (1988). His professional society memberships include the American Association for the Advancement of Science, Association of Molecular Pathology, American Society Human Genetics, American College Medical Genetics, American Association Cancer Research, American Society of Clinical Oncology and American Association for the Study of Liver Disease.