After years of research and clinical testing, we have developed non-invasive, accurate blood tests for early detection of cancer. By making cancer prevention routine, we enable everyone to take control of their own health. The more people take our breakthrough blood tests, the more lives we can save. Life over cancer.

Publications & Abstracts

ASCO Gastrointestinal Cancers Symposium, 2024

Multisite external validation of a blood test for colorectal neoplasia screening in a majority average-risk screening cohort of 449 subjects

Shai Friedland, Drew Watson, Douglas K. Rex, Ashish Nimgaonkar, Zhen Zhang, Alex Atkins, Ben Hsieh, Jr-Ming Lai, Stephen Su, Jen-Chia Wu, Hung-Jen Shao, Jessica Tesoriero, Lindsey Hannah, John McGowan, Daniel S. Mishkin, Ekta Gupta, Samir Gupta, John J. Sninsky, Rui Mei
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ASCO Gastrointestinal Cancers Symposium, 2023

Clinical performance of a multimodal screening blood test for advanced adenomas and CRC in an average-risk cohort of 1,038 participants

Shai Friedland, Drew Watson, Douglas K. Rex, Ashish Nimgaonkar, Zhen Zhang, Alex Atkins, Ben Hsieh, Jr-Ming Lai, Stephen Su, Jen-Chia Wu, Hung-Jen Shao, Jessica Tesoriero, Lindsey Hannah, John McGowan, Samir Gupta, John J. Sninsky, Rui Mei
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  • Gastro Hep Advances, 2021

    Development and Clinical Validation of a Blood Test for Early Detection of Colorectal Adenomas and Cancer for Screening and Post-Polypectomy Surveillance

    Shai Friedland, Drew Watson, Jennifer Pan, Yu Chen, Ashish Nimgaonkar, Zulfiqar Gulzar, Alexander Atkins, Pratyush Gupta, Julian Lucas, Jr-Ming Lai, Huangpin Hsieh, Stephen Su, Samir Gupta, John J. Sninsky, and Rui Mei
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  • Digestive Disease Week DDW, 2021

    A sensitive and quantitative non-invasive multimodal blood test that detects cancer and recapitulates adenoma prognosis available from colonoscopy

    Shai Friedland, Jennifer Y. Pan, Drew Watson, Yu Chen, Ashish Nimgaonkar, Zulfiqar Gulzar, Pratyush Gupta, Alexander Atkins, Jr-Ming Lai, Huangpin B. Hsieh, Stephen Su, Samir Gupta, John J. Sninsky, Rui Mei
    VIEW THE ABSTRACT
  • ASCO Gastrointestinal Cancers Symposium, 2021

    Development and clinical validation of a blood test for early detection of colorectal adenomas and cancer

    Shai Friedland, Jennifer Y. Pan, Drew Watson, Yu Chen, Ashish Nimgaonkar, Zulfiqar Gulzar, Pratyush Gupta, Alex Atkins, Jr-Ming Lai, Ben Hsieh, Stephen Su, Iris Ciu, Ploy Setthasap, John Sninsky, Rui Mei
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  • ASCO Annual Meeting, 2020

    A sensitive and quantitative multimodal blood test for the detection of colorectal adenomas and cancer: Correlation with size and number of polyps

    Shai Friedland, Jennifer Y. Pan, Drew Watson, Yu Chen, Ashish Nimgaonkar, Zulfiqar Gulzar, Pratyush Gupta, Julian Lucas, Alex Atkins, Jr-Ming Lai, Ben Hsieh, Stephen Su, Austin Lim, Iris Ciu, Ploy Setthasap, John J. Sninsky, Rui Mei
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  • Digestive Disease Week DDW, 2020

    A Highly Sensitive and Quantitative Multimodal Blood Test for the Detection of Colorectal Adenomas and Cancer

    Shai Friedland, Drew Watson, Jennifer Y. Pan, Yu Chen, Ashish Nimgaonkar, Zulfiqar Gulzar, Pratyush Gupta, Julian Lucas, Alexander Atkins, Jr-Ming Lai, Huangpin B. Hsieh, Stephen Su, Austin Lim, Iris Chu, Ploy Setthasap, John Sninsky, Rui Mei
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  • Journal of Circulating Biomarkers, 2019

    Analytical validation of the CellMax platform for early detection of cancer by enumeration of rare circulating tumor cells

    Pratyush Gupta, Zulfiqar Gulzar, Ben Hsieh, Austin Lim, Drew Watson, and Rui Mei
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  • Clinical and Translational Gastroenterology, 2019

    Novel Circulating Tumor Cell Assay for Detection of Colorectal Adenomas and Cancer

    Wen-Sy Tsai, Jeng-Fu You, Hsin-Yuan Hung, Pao-Shiu Hsieh, Ben Hsieh, Heinz-Josef Lenz, Gregory Idos, Shai Friedland, Jennifer Yi-Jiun Pan, Hung-Jen Shao, Jen-chia Wu, Jr-Ming Lai, Shih-En Chang, Rui Mei, Drew Watson, Manana Javey, and Ashish Nimgaonkar
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  • Molecular Diagnosis & Therapy, 2019

    Detection of Circulating Tumor DNA with a Single-Molecule Sequencing Analysis Validated for Targeted and Immunotherapy Selection

    Alexander Atkins, Pratyush Gupta, Bing Melody Zhang, Wen-Sy Tsai, Julian Lucas, Manana Javey, Anagh Vora, Rui Mei
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  • European Society for Medical Oncology, 2019

    Novel Blood Based Circulating Tumor Cell Biomarker For Breast Cancer Detection

    Chun-Yu Liu, Yi-Fang Tsai, Feng-Ming Lin, Jen-Chia Wu, Yen-Shu Lin, Ta-Chung Chao, Kuang-Liang King, Pei-Ju Lien, Jane Wang, Yung-Hui Lin, Yi-Chen Lai, Huangpin Hsieh, Anjay Saklecha, Jr-Ming Lai, Shih-En Chang, Mana Javey, Drew Watson, Rui Mei, Ling-Ming Tseng
    VIEW THE ABSTRACT
  • Cancer Immunology, Immunotherapy 2019

    Novel circulating tumor cell‑based blood test for the assessment of PD‑L1 protein expression in treatment‑naïve, newly diagnosed patients with non‑small cell lung cancer

    Chen, Y.L., Huang, W.C., Lin, F.M., Hsieh, H.B., Hsieh, C.H., Hsieh, R.K., Chen, K.W., Yen, M.H., Lee, J., Su, S. and Marfatia, T.
    VIEW THE PUBLICATION
  • ASCO Gastrointestinal Cancers Symposium, 2019

    Prospective Clinical Study of Circulating Tumor Cells For Colorectal Cancer Screening

    Podium Presentation On Circulating Tumor Cell Count From A Blood Sample For Colorectal Cancer (CRC) Prevention
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  • Biomaterials, July 2013

    Antibody conjugated supported lipid bilayer for capturing and purification of viable tumor cells in blood for subsequent cell culture.

    Foundational publication describing the proprietary CellMax CTC technology and its performance
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  • AACR ANNUAL MEETING 2018

    CTC and ctDNA Profiling to Detect 6 NCCN-Guideline Recommended Classes of Alterations For Immunotherapy and Targeted Therapy Selection Using Sample From a Single Blood Draw

    Huangpin B. Hsieh, Jen-chia Wu, Feng-Ming Lin, Julian Lucas, Alex Atkins, Pratyush Gupta, Hung-Jen Shao, Yen-Lin Chen,Wen-Jie Huang, Chia-Hsun Hsieh, Ruey Kuen Hsieh, Kuo-Wei Chen, Ming-Hong Yen, Mana Javey, Shih-En Chang, Twinkal Marfatia, Drew Watson, Mahul Amin, Ashish Nimgaonkar, Oscar Segurado, Rui Mei
    VIEW THE ABSTRACT
  • AACR ANNUAL MEETING 2018

    Analytical validation of a novel circulating tumor DNA detection platform for targeted and immunotherapy selection

    Pratyush Gupta, Julian Lucas, Alex Atkins, Wen-Sy Tsai, Twinkal Marfatia, Shih-En Chang, Oscar Segurado, Rui Mei
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  • AACR ANNUAL MEETING 2018

    Comparison of rare pathogenic germline variants associated with cancer predisposition syndrome in Taiwan and USA populations

    Zulfiqar Gulzar, Julian Lucas, Alex Atkins, Stephen Su, Oscar Segurado, Rui Mei
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  • ASCO GENITOURINARY CANCERS SYMPOSIUM 2018

    Prospective Clinical Study of a Prostate Cancer (PCa) Rule-Out Blood Test for PSA Gray Zone Patients Using a Sensitive Circulating Tumor Cell Assay

    See-Tong Pang, Ying-Hsu Chang, Po-Hung Lin, Ying Chang, Drew Watson, Oscar Segurado, Si-Hong Lu, Jen-chia Wu, Jr-Ming Lai, Hung-Jen Shao, Shih-En Chang, Ben Hsieh, Mana Javey, Rui Mei
    VIEW THE ABSTRACT
  • CASE REPORTS IN ONCOLOGY, 2018

    CSF-ctDNA SMSEQ Analysis to Tailor the Treatment of a Patient with Brain Metastases: A Case Report

    Wen-Tsung Huang, Na-Mi Lu, Wen-Yuan Hsu, Shih-En Chang, Alex Atkins, Rui Mei, Manana Javey
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  • LIQUID BIOPSY SUMMIT 2016

    Genomic Profiling of Tumors For Targeted Therapy Matching Using Novel Liquid Biopsy Platform (SMSEQ)

    Wen-Sy Tsai, Shan-Fu Wu, Julian Lucas, Gangwu Mei, Mana Javey, Rui Mei
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  • CANCER BIOLOGY AND THERAPY 2016

    Identifying Cancer Origin Using Circulating Tumor Cells

    Si-Hong Lu, Wen-Sy Tsai, Ying-Hsu Chang, Teh-Ying Chou, See-Tong Pang, Po-Hung Lin, Chun-Ming Tsai, Ying-Chih Chang
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  • NATURE SCIENTIFIC REPORTS 2016

    Circulating Tumor Cell Count Correlates with Colorectal Neoplasm Progression and Is a Prognostic Marker for Distant Metastasis in Non-Metastatic Patients

    Wen-Sy Tsai, Jinn-Shiun Chen, Hung-Jen Shao, Jen-Chia Wu, Jr-Ming Lai, Si-Hong Lu, Tsung-Fu Hung, Yen-Chi Chiu, Jeng-Fu You, Pao-Shiu Hsieh, Chien-Yuh Yeh, Hsin-Yuan Hung, Sum-Fu Chiang, Geng-Ping Lin, Reiping Tang, Ying-Chih Chang
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  • PLOS 2016

    Sensitive and Specific Biomimetic Lipid Coated Microfluidics to Isolate Viable Circulating Tumor Cells and Microemboli for Cancer Detection

    Jia-Yang Chen, Wen-Sy Tsai, Hung-Jen Shao, Jen-Chia Wu, Jr-Ming Lai, Si-Hong Lu, Tsung-Fu Hung, Chih-Tsung Yang, Liang-Chun Wu, Jinn-Shiun Chen, Wen-Hwa Lee, Ying-Chih Chang
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  • TJCC 2016

    Genomic Profiling of Tumors Using Liquid Biopsy to Match Patients to Best Treatment Options

    Wen-Sy Tsai, Shan-Fu Wu, Julian Lucas, Gangwu Mei, Mana Javey, Rui Mei
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  • TJCC 2016

    An Innovative Platform for Early Detection of Circulating Tumor Cells for Colorectal Cancer

    Wen-Sy Tsai, Ying-Chih Chang, Ben Hsieh, Hung-Jen Shao, Jen-chia Wu, Jr.-Ming Lai, Mana Javey, Rui Mei
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  • BIOMICROFLUIDICS 2014

    Efficient elusion of viable adhesive cells from a microfluidic system by air foam

    Jr-Ming Lai, Hung-Jen Shao, Jen-Chia Wu, Si-Hong Lu, and Ying-Chih Chang
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  • BIOMATERIALS 2013

    Antibody Conjugated Supported Lipid Bilayer for Capturing and Purification of Viable Tumor Cells in Blood

    Jen-Chia Wu, Po-Yuan Tseng Wen-Sy Tsai, Mei-Ying Liao, Si-Hong Lu, Curtis W. Frank, Jinn-Shiun Chen, Han-Chung Wu, Ying-Chih Chang
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  • BIOMACROMOLECULES, 2010

    Type I Collagen-Functionalized Supported Lipid Bilayer as a Cell Culture Platform

    Chun-Jen Huang, Nam-Joon Cho, Chih-Jung Hsu, Po-Yuan Tseng, Curtis W. Frank, Ying-Chih Chang
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  • BIOMACROMOLECULES 2010

    Selection, Enrichment, and Maintenance of Self-Renewal Liver Stem/Progenitor Cells Utilizing Polypeptide Polyelectrolyte Multilayer Films

    Hsuan-Ang Tsai, Ruei-Ren Wu, I-Chi Lee, Hsiao-Yuan Chang, Chia-Ning Shen, Ying-Chih Chang
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