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Colonoscopy has high sensitivity for the detection of adenomas. Unfortunately, compliance with colonoscopy is less than 40%.4 There are non-invasive testing options, both stool- and blood-based. However, they have low sensitivity for the detection of precancerous adenomas. As a result, 60% of colorectal cancer is diagnosed after it is no longer localized,5 when survival rates are low.
Colorectal cancer is the second largest cancer killer in the United States.6