THURSDAY, Jan. 18, 2018 (U.S. News & World Report/HealthDay News)
A simple, cheap blood test to detect colon cancer — even in its early stages — appears highly effective and accurate, new research indicates.
SUNNYVALE, CALIF. (PRWEB) MARCH 28, 2018
CellMax Life, a leading cancer diagnostics company enabling early cancer detection with affordable non-invasive blood tests, announced today the U.S. launch of a blood test to detect the expression of PD-L1 – a key protein involved in suppressing the immune system – in circulating tumor cells (CTCs). Since immunotherapies work only on a minority of patients, identifying cancer patients expressing the PD-L1 protein in CTCs can help determine if they will benefit from the treatment, sparing significant costs and potential side effects.
A study on early and late stage lung cancer patients was recently completed, and the data will be shared at the upcoming American Association for Cancer Research (AACR) conference in Chicago on April 14 through 18. The test was able to capture CTCs for PD-L1 testing in blood in about 90 percent of tested patients. Conversely, tissue can be insufficient or unavailable for testing in 25 to 50 percent of advanced lung cancer patients. About 50 percent of the CTC tested patients were PD-L1 positive; this is consistent with previously reported PD-L1 positivity rates in clinical studies.
Dr. David Gandara, oncologist and director of the Thoracic Oncology Program at University of California, Davis, said: “PD-L1 testing by immunohistochemistry is a standard of care as a predictive biomarker for checkpoint immunotherapy. Blood-based testing offers three potential advantages. First, about 25 percent of patients have inadequate tumor tissue upfront to test for both molecular biomarkers and PD-L1. Second, PD-L1 is a dynamic biomarker, which can change over time, so using tumor from a prior biopsy may be misleading. PD-L1 can also be unevenly distributed in tissue, leading to a false negative and denying patients the opportunity to receive immunotherapy. Lastly, looking to the future, blood-based testing provides a means for repeat testing and timely monitoring, which would not be possible otherwise. A PD-L1 blood test can overcome current issues and would be an attractive alternative to tissue testing.”
“For the 1.7 million people diagnosed with cancer annually in the United States, and the 14.8 million people living with cancer there is no affordable, non-invasive and effective way to monitor patients for treatment response or cancer recurrence,” said Atul Sharan, CEO of CellMax Life. “With the invasiveness of tissue testing and high costs and limitations of existing DNA-based liquid biopsies, conducting repeat testing has been impractical, and often, impossible. CellMax CTC blood tests offer a solution to this major unmet need. We are also seeing a lot of interest from biopharmaceutical companies who want to partner with us to de-risk their clinical trials by using CTCs to monitor patients and identify non-responders to their drug early.”
CellMax Life also analyzes circulating tumor DNA (ctDNA) in the blood sample. The combination of DNA and CTC analysis makes the CellMax liquid biopsy the first and only blood test that includes all mutation classes recommended in the guidelines of the National Comprehensive Cancer Network (NCCN) for immunotherapy and targeted therapy selection in patients with advanced solid tumors.
About CellMax Life
CellMax Life is a leading cancer diagnostics company whose mission is to transform how cancer is diagnosed and managed with globally affordable non-invasive tests for early cancer detection and management. CellMax Life’s unique expertise in circulating tumor cells (CTC) and next generation sequencing (NGS) of DNA, as well as circulating tumor DNA (ctDNA) has enabled it to offer highly effective precision medicine solutions for healthy people, as well as patients diagnosed with cancer.
CellMax Life’s tests include CellMax-DNA Hereditary Cancer Risk Test, CellMax-CRC Colorectal Cancer Screening Test, CellMax-Prostate Cancer Test, CellMax-LBx Liquid Biopsy for immunotherapy and targeted therapy selection and CellMax-PanCa Monitoring Test. All clinical testing is performed at CLIA and CAP accredited laboratories in Sunnyvale, California and Taipei, Taiwan.
For additional information, please visit http://www.cellmaxlife.com.
Wall Street Journal, March 16, 2018 7:30 a.m. ET
Theranos, formed in 2003, climbed to a valuation of more than $9 billion, partly by telling investors it had developed a portable blood analyzer that could conduct the full range of laboratory tests using only finger drops of blood. Along the way, the company enforced what some former employees described as a culture of secrecy, and some employees were leery about the accuracy of its technology, The Wall Street Journal has reported.
Founded by Elizabeth Holmes, Theranos has been under scrutiny since the Journal reported in October 2015 that the company relied heavily on other companies’ instruments and used its linchpin lab machine in only a small portion of the tests sold to consumers. Regulators began investigating soon after, and on Wednesday, the Securities and Exchange Commission said it had filed civil fraud charges against Ms. Holmes,
Theranos and its former president. The SEC accused them of raising more than $700 million from investors through “an elaborate, yearslong fraud in which they exaggerated or made false statements about the company’s technology, business, and financial performance.” To settle the charges, Ms. Holmes has agreed to pay a $500,000 fine and has been stripped of voting control over the company. She is also barred from being an officer or director of a public company for 10 years.
The SEC settled charges with Theranos and Ms. Holmes but not with Theranos’s former president, Ramesh “Sunny” Balwani. Mr. Balwani’s lawyer, Jeffrey B. Coopersmith, said in a statement: “Sunny Balwani accurately represented Theranos to investors to the best of his ability. He believed in the potential and mission of the company and its technology to promote transparency and benefit people by empowering them with access to their own health care information at a low cost.” The Newark, Calif., company and Ms. Holmes neither admitted nor denied the SEC allegations, the agency said.
“The company is pleased to be bringing this matter to a close and looks forward to advancing its technology,” Theranos’s independent directors said in a statement. Investors and entrepreneurs said cases of alleged fraud must have consequences. Successful life-sciences entrepreneurs, they said, usually have significant clinical, research or corporate expertise, and medical startups must publish their research data to establish themselves. In hindsight, Theranos’s business proposition might have been more solid had Ms. Holmes first worked at a large blood-testing company where she was tasked with finding and developing new technology, said Kevin Kinsella, founder of technology and biopharma investor Avalon Ventures, which didn’t invest in Theranos. He said Theranos’s claims about its technology seemed outlandish from the start. “This was fraud from the get-go,” Mr. Kinsella said. When backing entrepreneurs, he added, “We look for someone who’s done it before with someone else’s money.” Some entrepreneurs said too much hype for unproven technology can hurt budding sectors by creating unrealistic expectations.
“There should not be any shortcuts when it comes to bringing a product to market in medicine,” Atul Sharan, chief executive of cancer-diagnostics startup CellMax Life, said in an email. “Our eye has to always be on the patient, not the dollar sign.” CellMax pursues an emerging approach to cancer testing that involves scanning for markers in the blood known as circulating tumors cells and circulating tumor DNA.
Tom Rodgers, who leads McKesson Ventures, which didn’t invest in Theranos, said via an email that his firm isn’t doing anything different in the wake of the Theranos fallout,adding that most traditional, early-stage health-care-only venture capitalists already perform fairly robust diligence. Added Mr. Rodgers: “It would be a big red flag if a CEO said, ‘We can’t show you our secret sauce.’”
The test detects so-called “circulating tumor cells” (CTCs). Researchers tested it on 620 people in Taiwan who were scheduled for a routine colonoscopy at a local hospital.
By comparing the blood test results with the colonoscopy results, the study team found that the blood test identified colon cancer in 87 percent of cases, ranging from stage I to stage IV cancer. The blood test also was able to detect 77 percent of pre-cancerous lesions indicating early stage disease. The researchers described the test as highly accurate, noting that it correctly identified cancer 84 to 88 percent of the time. Less than 3 percent of the time did it produce a “false positive” result, which mistakenly indicates the presence of cancer when there is none.
“Because the test can easily be made available for under $150, it could potentially be offered directly to consumers and ordered by physicians, with colonoscopy being the confirmatory diagnostic,” said study author Dr. Ashish Nimgaonkar.
The test is not yet available in the United States. If and when it does come to market, he said, it probably would not replace colonoscopy as the gold standard for screening. Rather, it most likely would supplant the preliminary stool-based tests that people often are reluctant to use, Nimgaonkar said. “This test could be an option for such individuals, boosting compliance” because it has a “higher sensitivity” than the stool-based screening options now available, he said.
Nimgaonkar is a gastroenterologist and medical director of Johns Hopkins University’s Center for Bioengineering Innovation and Design, in Baltimore. He and his colleagues are scheduled to present their findings Jan. 20 in San Francisco at the American Society of Clinical Oncology’s Gastrointestinal Cancers Symposium.
Experts note that research presented at meetings should be considered preliminary because it has not been subjected to the rigorous scrutiny given to research published in medical journals. Of the 620 people, all older than 20, included in the study, 438 were found to have either pre-cancerous growths, known as polyps, or colorectal cancer ranging from early to late-stage in development. For the blood test, the researchers used about a half-teaspoon of each participant’s blood. Earlier research had indicated that the test could detect very small amounts of CTCs — as low as one CTC per billion blood cells — with that size blood sample.
The researchers calculated that the blood test’s accuracy had a “specificity value” of more than 97 percent — meaning that any result indicating the presence of cancer or pre-cancer lesions should be considered very reliable.
Still, Nimgaonkar stressed that the blood test is envisioned as another tool in the screening arsenal rather than a replacement for colonoscopies.
“Just like stool tests, this test would not replace diagnostic colonoscopies,” he said. Those “would still be the confirmatory diagnostic for positive patients and would be needed for tumor or polyp biopsy and removal and examination if a person has a positive CTC test.”
Nimgaonkar said that planning is underway to launch the test in the United States, and he expects it to become available sometime this year.
Dr. Andrew Chan offered a more tempered take on the test’s potential. He’s a professor of medicine at Harvard Medical School and a gastroenterologist at Massachusetts General Hospital in Boston.
“These early results appear promising, but the sensitivity of the test is still not optimal. The number of patients in the study is also relatively small,” Chan said.
“In the long-term, there is the possibility that this type of liquid biopsy method could be used for screening,” he said. “However, I think it will require the development of more sensitive techniques tested in larger populations of patients before it will be a plausible alternative to current screening approaches.”
More information
The U.S. National Cancer Institute has more on colon cancer screening.
Copyright © 2018 HealthDay. All rights reserved.
THURSDAY, Jan. 18, 2018, 11:06 P.M. E.S.T. (New York Times/The Associated Press)
Scientists are reporting progress on a blood test to detect many types of cancer at an early stage, including some of the most deadly ones that lack screening tools now.
Many groups are working on liquid biopsy tests, which look for DNA and other things that tumors shed into blood, to try to find cancer before it spreads, when chances of cure are best.
In a study Thursday in the journal Science, Johns Hopkins University scientists looked to see how well their experimental test detected cancer in people already known to have the disease. The blood tests found about 70 percent of eight common types of cancer in the 1,005 patients. The rates varied depending on the type — lower for breast tumors but high for ovarian, liver and pancreatic ones. In many cases, the test narrowed the possible origin of the cancer to one or two places, such as colon or lung, important for limiting how much follow-up testing a patient might need. It gave only seven false alarms when tried on 812 others without cancer.
The test is nowhere near ready for use yet; it needs to be validated in a larger study already underway in a general population, rather than cancer patients, to see if it truly works and helps save lives — the best measure of a screening test’s value. “We’re very, very excited and see this as a first step,” said Nickolas Papadopoulos, one of the Hopkins study leaders. “But we don’t want people calling up” and asking for the test now, because it’s not available, he said. Some independent experts saw great promise. “It’s such a good first set of results” that it gives hope this approach will pan out, said Dr. Peter Bach, a health policy expert at Memorial Sloan Kettering Cancer Center who consults for a gene testing company. “Anything close to 50 percent or 40 percent detection is pretty exciting stuff,” and this one did better than that, he said. Dr. Len Lichtenfeld, deputy chief medical officer of the American Cancer Society, was encouraged that the test did well on cancers that lack screening tests now. If a blood test could find 98 percent of ovarian cancers at an early stage, as these early results suggest, “that would be a significant advance,” he said. But he cautioned: “We have a long way to go to demonstrate its effectiveness as a screening test.”
TESTING THE TEST
The test detects mutations in 16 genes tied to cancer and measures eigh proteins that often are elevated when cancer is present.nIt covers breast, colon and lung and five kinds that don’t have screening tests for people at average risk: ovarian, liver, stomach, pancreatic and esophageal. Prostate cancer is not included. A blood test already is widely used — the PSA test — but its value for screening is controversial. Researchers tried the new test on people whose cancers were still confined to where it started or had spread a little but not widely throughout the body. It detected 33 percent of breast cancers, about 60 percent of colon or lung cancers and nearly all of the ovarian and liver ones. It did better when tumors were larger or had spread. It did less well at the very earliest stage.
CAVEATS AND NEXT STEPS
The test probably will not work as well when tested in a general population rather than those already known to have cancer, researchers say. Hopkins and Geisinger Health System in Pennsylvania have started a study of it in 10,000 Geisinger patients who will be tracked for at least five years. The work was financed by many foundations, the Mayo Clinic, the National Institutes of Health and Howard Hughes Medical Institute, which provides The Associated Press with funding for health and science coverage. Many study leaders have financial ties to gene testing companies, and some get royalties for patents on cancer detection methods. Researchers say the test could cost around $500 based on current materials and methods, but the ultimate goal is to commercialize it, so what a company would charge is unknown.
OTHER LIQUID BIOPSY NEWS
Also this week, Taiwan-based CellMax Life gave results on its liquid biopsy test, which looks for whole tumor cells shed into blood, at an American Society of Clinical Oncology conference. Researchers tested 620 people getting colonoscopies or with confirmed colon cancer at a hospital in Taiwan. The company said its test had an overall accuracy of 84 to 88 percent for detecting cancer or precancerous growths and a false alarm rate around 3 percent. The company’s chief executive, Atul Sharan, said U.S. studies should start this year. The test is sold now in Taiwan for $500, but should cost around $150 in the U.S., he said. Dr. Richard Schilsky, chief medical officer of the oncology society, said results are encouraging, but the test needs more study, especially to see if it gives too many false alarms. “The last thing you’d want is a test that tells you you might have cancer if you don’t,” he said.
___
This Associated Press series was produced in partnership with the Howard
Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.
© 2018 The New York Times Company
New test could potentially be offered at less than $150 enabling high compliance and global adoption
SUNNYVALE, Calif., Jan. 17, 2018 /PRNewswire/ — CellMax Life, a leading cancer diagnostics company enabling early cancer detection and management with globally affordable non-invasive blood tests, today announced results from a new study showing that its circulating tumor cell (CTC) blood test, based on its proprietary CMxTM platform, can detect colorectal cancer at an early stage – and in many cases, pre-cancerous lesions – with accuracy ranging from 84 to 88 percent.
Colorectal cancer is among the most preventable cancers when detected early. Yet, it is the second leading cancer killer in the United States. Traditional methods like colonoscopies and stool-based tests are invasive or inconvenient. For these reasons, compliance with colorectal cancer screening remains low, leading to most colorectal cancers being detected in late stages, when survival rates are poor.
“The positive results of this study prove that the CellMax CTC blood test can address the unmet need for a convenient and accurate test for early colorectal cancer detection; since the test only requires a routine blood draw, it can be easily integrated into a patient’s regular physical exam, increasing compliance,” said study co-author Ashish Nimgaonkar, MD, a gastroenterologist and medical director at the Center for Bioengineering Innovation & Design at Johns Hopkins University. “Additionally, research conducted by the American Cancer Society and Centers for Disease Control and Prevention states that test affordability is the number one reason patients cite for not undergoing regular screening for colorectal cancer. This blood test could potentially be offered between $100 and $150.”
CTCs are cancer cells that detach from a primary tumor and circulate through the bloodstream and are a fundamental mechanism of metastasis. CTCs have long been known to be valuable in cancer detection, but most technologies using CTCs are only able to detect late-stage cancer. The CellMax CTC blood test “liquid biopsy” detects these CTCs in the blood at the earliest stages. This is one of the first clinical studies to show that CTCs can be useful for detecting early, more treatable stages of cancer.
The researchers enrolled 620 people over the age of 20 who were either visiting the hospital for routine colonoscopies or had confirmed colorectal cancer. After a colonoscopy and biopsy, 438 people were found to have either adenomatous polyps (pre-cancerous growths) or early to late-stage colorectal cancer. The remaining study participants had no signs of pre-cancerous growths or colorectal cancer and were the comparison group.
Two milliliters (about half a teaspoon) of peripheral whole blood were tested from each subject for CTC analysis through a routine blood draw. The blood samples were then processed through the CMx platform. The results of these assays were then compared in a blinded analysis with the colonoscopy results.
The study results showed that the test’s sensitivity ranged from 77 percent for detection of CTCs in pre-cancerous lesions to 87 percent for stage I-IV cancers. The accuracy of the results, taking into account both sensitivity and specificity, was high and ranged from 84 to 88 percent for pre-cancerous and cancerous samples. Additionally, the accuracy of this test was superior to that of fecal occult blood testing (FOBT), a guideline-recommended stool test for colorectal cancer screening.
“Early detection is perhaps the only real cure for cancer. To be effective, tests for early cancer detection need to be non-invasive, easy, highly affordable and accurate, and our CTC blood test meets all of these requirements,” said Atul Sharan, co-founder and CEO of CellMax Life. “Recent surveys reveal a preference for blood tests over stool-based screening tests in more than 80 percent of patients who did not undergo invasive colonoscopy screening. This test can be an option for these individuals and boost compliance.”
The authors are planning more studies in Taiwan and will be extending the studies to the United States. The fundamental mechanism of circulating tumor cell shedding, and the capture using the CMx platform, are the same across all solid tumors. Thus, this platform is expected to provide favorable results for other solid tumors such as breast, lung and prostate cancers.
The data from the study, sponsored by Taiwan’s Ministry of Health and its largest hospital, the Chang Gung Memorial Hospital, will be presented by lead author, Dr. Wen-Sy Tsai (MD, Ph.D.) at the 2018 ASCO Gastrointestinal Cancers Symposium on Saturday, January 20. Attendees can also visit CellMax Life at booth #27 at the conference to learn more about the CellMax CTC blood test for colorectal cancer and the study’s results.
About CellMax Life
CellMax Life is a leading cancer diagnostics company whose mission is to transform how cancer is diagnosed and managed with globally affordable non-invasive tests for early cancer detection and management. CellMax Life’s unique expertise in circulating tumor cells (CTC) and next generation sequencing (NGS) of DNA, as well as circulating tumor DNA (ctDNA) has enabled it to offer highly effective precision medicine solutions for healthy people, as well as patients diagnosed with cancer.
CellMax Life’s tests include CellMax-DNA Hereditary Cancer Risk Test, CellMax-CRC Colorectal Cancer Screening Test, CellMax-Prostate Cancer Test, CellMax-LBx Liquid Biopsy for immunotherapy and targeted therapy selection and CellMax-PanCa Monitoring Test. All clinical testing is performed at CLIA and CAP accredited laboratories in Sunnyvale, California and Taipei, Taiwan.
For additional information, please visit www.cellmaxlife.com.
Antenna Group
Nathan Molinari (Media Contact)
CellMaxLife@antennagroup.com
201-465-8047
CellMax Life’s Precision, Non-Invasive Cancer Testing Now Available throughout Southeast Asia through Asia Genomics
CellMax and Asia Genomics Enter Broad Partnership to Serve Southeast Asia
Singapore and Sunnyvale, CA, July 11, 2017 — Asia Genomics, Southeast Asia’s leading clinical laboratory is partnering with Silicon Valley-based CellMax Life to immediately introduce CellMax Life’s multi-biomarker precision oncology blood and saliva tests across Southeast Asia. The advanced diagnostic testing will reduce cancer mortality through personalized, precision cancer risk assessment and screening in the Philippines, Vietnam, Malaysia, Thailand, and Singapore.
Affordable Precision Testing Gives Individuals Achieve More Control
According to the GLOBOCAN database, the ratio of cancer deaths to the number of new cancer cases in Asia was 0.66, twice that of North America (0.33). Only in Africa were cancer patients more likely to die (0.73). This an indication that cancer is not diagnosed until later stages in Asia, when it becomes difficult to treat effectively.
Individuals and their families no longer need to be passive about their health in the face of these risks — the Asia Genomics and CellMax Life partnership will give everyone more control over their health. Asia Genomics will immediately make available CellMax Life’s affordable personalized and precision cancer risk assessment and screening through various hospitals and clinics throughout Southeast Asia, and, where appropriate, direct to consumer.
Individuals can now achieve the earliest possible cancer detection and treatment by assessing their risk of cancer and doing more frequent screening through the non-invasive blood tests, so that they can undertake timely measures if cancer is diagnosed. In a complementary manner, Oncologists using the non-invasive blood tests will be able to more accurately assess the risk of cancer relapse, and offer personalized treatments to patients.
Next Generation Techniques Deliver Affordable, Precision Cancer Testing
The CellMax tests uniquely combine proprietary and clinically proven technologies that have been tested in Asia:
1. CellMax-DNA Genetic Cancer Risk Test — a simple saliva DNA test to identify hereditary cancer risk. The test provides an affordable and accessible saliva test to identify an individual’s cancer pre-disposition, to help them preempt worst case scenarios. It examines 98 genes across 25 hereditary cancers — currently the broadest gene panel on the market — offering highest quality, fastest turnaround time and affordable price. The largest possible number of individuals and families can for the first time better understand their risk of cancer, and then work with their doctors for a customized screening and lifestyle plan.
Hereditary gene mutations can increase the risk of cancer by 20 times. The test surveys for increased risk of some of the most common cancers in Southeast Asia: lung, liver, colorectal, prostate and stomach, along with bladder, lip, pancreas, breast, ovary and others.
2. CellMax-CRC Test — a non-invasive Circulating Tumor Cell (CTC) blood test that provides an early warning for Colorectal cancer.
Frequent screening to detect cancer early is the best prevention against the worst outcomes of the disease.
This non-invasive test, can be expected to dramatically increase compliance with recommended screening levels, and allow people to tailor the testing frequency to suit their risk.
Additionally, Asia-Genomics’ wide network of providers, leading oncologists, and support teams enable this precision cancer testing and support to be broadly accessible to every individual in South-East Asia.
“A major goal of Asia Genomics is to reduce cancer mortality in Southeast Asia, by offering convenient and affordable testing” said Dr. Wong Mun Yew, Founder & CEO, Asia Genomics. “Accuracy remains critical, and CellMax Life has made tremendous advances in precision analysis of key biomarkers, including CTCs which are pre-cursors to ctDNA.”
“CellMax Life is bringing early, non-invasive DNA and CTC-based cancer detection and management via affordable, accessible, accurate cancer saliva and blood tests,” said Atul Sharan, President and CEO. “Asia Genomics is unique in Asia – it has an unparalleled reputation, and strong relationships in the medical community across multiple countries. Their priority on making next generation cancer diagnostics, that works for Asians, highly accessible makes them an ideal fit with our vision.”
About Asia Genomics
Asia Genomics is a leading molecular diagnostics company focused on molecular biology and genomics to transform the healthcare industry in Asia. The Company offers tests that are evidence-based, accepted and endorsed by doctors internationally. Based in Singapore, with operations in Malaysia, Philippines, Vietnam, Indonesia, China, Hong Kong and Thailand, Asia Genomics has two laboratories, and a total market reach of more than 1.5 billion people. www.asia-genomics.com
About CellMax Life
CellMax Life, Inc. is a precision cancer blood-testing company providing comprehensive, personalized multi-biomarker technology platforms for affordable and accessible genetic cancer risk assessment, early detection, recurrence and personalized treatment of cancer. CellMax Life’s products include CellMax-DNA Genetic Cancer Risk Test Assure, CellMax-OncoLBx Liquid Biopsy, and CellMax-CRC Colorectal Cancer Early-Detection. www.cellmaxlife.com
CellMax Life Receives Grant from Taiwan Government for CTC Cancer Early Detection System
Non-Invasive Cancer Screening Investment Furthers CellMax’s Precision Oncology Testing Leadership
Sunnyvale, CA – June 14, 2017 – CellMax Life, the precision cancer testing company, today announced it has received a $NT 23 million grant from the Taiwan Government Industrial Development Bureau (IDB) Ministry of Economic Affairs. CellMax Life will use the grant to accelerate the automation and world-wide commercialization of its proven early cancer detection circulating tumor cell (CTC) proprietary CellMax CMxTM platform.
The prestigious IDB grant is awarded to a few selected companies, following an extensive application and review process involving experts from industry and academia. The grant is a key tool in the Taiwan government’s plan to accelerate development of high value-added technology.
“This is additional recognition that our CTC Technology is enabling early cancer detection in the high-growth cancer diagnostics area,” said Atul Sharan, president & CEO of CellMax Life. “We are thankful to the IDB for their proactive investment, which will help CellMax become a world leader in this important sector.”
Sharan continued, “These funds will allow CellMax Life to more rapidly expand availability of its CTC CMxTM platform throughout the world, enabling affordable and frequent screening to reduce cancer mortality.”
CellMax CRC Screening for Early Cancer Detection
CellMax Life provides clinically-proven early cancer detection using next generation technology to detect circulating tumor cell biomarker in the blood. CTCs enable the earliest possible cancer detection, as they are precursors to circulating tumor cell DNA (ctDNA) biomarkers.
CellMax CMx platform has been clinically proven on thousands of patients, and is initially being applied to the CellMax-CRC Colorectal Cancer early detection product, with a goal to improving CRC screening compliance for the high-risk population and those over age 50.
For high-risk patients, the clinical studies showed that approximately 90% of the time, the CMx Platform correctly identified the patients who had colorectal cancer.
Additionally, by offering an affordable, high accuracy, non-invasive blood test as an early warning system, CellMax hopes to tangibly increase the early-stage detection when cancer is most curable. The same technology will be applied to other cancers as development continues. For more information, please visit CellMax-CRC colorectal cancer screening.
About CellMax Life
CellMax Life, Inc. is a precision cancer blood-testing company providing comprehensive, personalized multi-biomarker technology platforms for genetic cancer risk assessment, early detection and personalized treatment of cancer. CellMax Life’s products include CellMax-DNA Genetic Cancer Risk Test, CellMax-LBx Liquid Biopsy, and CellMax-CRC Colorectal Cancer Screening. For more information, please visit www.cellmaxlife.com, tw.cellmaxlife.com, or call +1 650-564-3905 (U.S.), or (+886) 0800-555-885 (Taiwan). Offices are at: 1271 Oakmead Parkway, Sunnyvale, CA 94085 and 18F-1 Park Street, Nangkang, Taipei City.
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